Publicaciones volver
Apoptosis in the trabecular meshwork of glaucomatous patients.
| Tipo: | Artículo |
| Autores: | Baleriola J, García-Feijoo J, Martínez-de-la-Casa JM, Fernández-Cruz A, de la Rosa EJ, Fernández-Durango R. |
| Títuto Revista: | Molecular Vision |
| Referencia: | |
| Centro: | 06 - UCM - IIORC |
Apoptosis in the trabecular meshwork of glaucomatous patients.
Source
3D Lab (Development, Differentiation, & Degeneration), Department of Cellular and Molecular Physiopathology, Centro de Investigaciones Biológicas, CSIC, Madrid, Spain.
Abstract
We established and validated an in toto method to perform TdT-mediated dUTP nick end labeling to study apoptosis in human trabecular meshwork tissue obtained during trabeculectomy in glaucoma patients. In specimens from patients with primary open-angle glaucoma and primary angle-closure glaucoma, we detected a tendency for more apoptotic cells to accumulate in patients with primary open-angle glaucoma. The utility of this method to study apoptosis in the trabecular meshwork is discussed, as well as its application as a tool in biologic samples.
- PMID: 18728789 [PubMed - indexed for MEDLINE]
- PMCID: PMC2518170
Images from this publication.See all images (2) Free text
